Beilstein J. Nanotechnol.2021,12, 633–664, doi:10.3762/bjnano.12.52
of patches of a silicon nitride membrane that were subsequently perforated by helium ion beam milling to create solid-state nanopores for biomoleculedetection. Following this approach, a low fluorescence background was achieved, facilitating the translocation detection of fluorescently labeled
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Figure 1: (a) Schematic diagram of the helium ion microscope. Adapted with permission from Cambridge Universi...
Beilstein J. Nanotechnol.2019,10, 975–984, doi:10.3762/bjnano.10.98
functionalization protocol is based on the non-covalent bonding of streptavidin on hydrophobic graphene surfaces. The two protocols end with the effective bonding of biotinylated anti-IgG antibodies to the streptavidin, which leaves the surface of the devices ready for possible IgG detection.
Keywords: biomolecule
detection; graphene integration; gravimetric biosensor; surface functionalization; Introduction
Gravimetric biosensors based on microscale mechanical or electromechanical resonators have attracted significant interest in recent years mainly due to the high sensitivity and selectivity they can attain if
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Figure 1:
3D AFM image of the surface of the Ni film: a) as grown, b) after graphene growth with a high heati...